The point of the whole exercise is to get the rifle on the paper at 25 yards, which will result in a hit on the target at 100 yards, shooting close enough to easily refine the zero.
I mean, who can miss a foot square target at 25 yds, right?
The next step, is at 100 yards, where you sight in ~2 1/2 - 3 in. high so theoretically, the bullet doesn't travel more than +- 3 inches above or below the point of aim out to what is called "point blank range", which is amazingly similar for a large variety of cartridges...iirc, less than 20 yards.
theoretically, this should keep your bullets within a 6 in circle on your target, resulting in a fatal hit with a center of body hold from the muzzle to in excess of 250 yards. Try it, you may like it!
That's what all the hoo ha surrounding the "rangefinding" scope reticles is all about. Hit easier.
I find them less than useful.
Actually, on my Burris Fullfield II, they are too small to be much assistance. But, that's just me.
Know your gun and load, sight in 2.5-3 in. high at 100 yards, and FEAR NOT! Ka POW! gottim!